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PF-3758309 hydrochloride

CAS No. 1279034-84-2

PF-3758309 hydrochloride ( —— )

产品货号. M17237 CAS No. 1279034-84-2

PF-3758309, also known as PF-03758309, is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥405 有现货
5MG ¥599 有现货
10MG ¥972 有现货
25MG ¥1547 有现货
50MG ¥2851 有现货
100MG ¥4479 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    PF-3758309 hydrochloride
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    PF-3758309, also known as PF-03758309, is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity.
  • 产品描述
    PF-3758309, also known as PF-03758309, is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PAK4 inhibitor PF-03758309 binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation, and survival.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    PAK4; PAK1; PAK6; PAK5; PAK3
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1279034-84-2
  • 分子量
    527.08
  • 分子式
    C25H31ClN8OS
  • 纯度
    98%
  • 溶解度
    ——
  • SMILES
    Cl.CN(C)C[C@@H](NC(=O)N1Cc2c(n[nH]c2Nc2nc(C)nc3ccsc23)C1(C)C)c1ccccc1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Briz V, Baudry M.2014 Feb 25;5:22. doi: 10.3389/fendo.2014.00022. eCollection 2014. PubMed PMID: 24611062; PubMed Central PMCID: PMC3933789.
产品手册
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